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Yutopar S.R: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Yutopar S.R - General Information

Adrenergic beta-agonist used to control premature labor. [PubChem]

 

Pharmacology of Yutopar S.R

Beta-2 adrenergic receptors are located at sympathetic neuroeffector junctions of many organs, including uterus. Yutopar S.R is beta-2 adrenergic agonist. It stimulates beta-2 adrenergic receptor, increases cAMP level and decreases intracellular calcium concentration. The decrease of calcium concentration leads to a relaxation of uterine smooth muscle.

 

Yutopar S.R for patients

Patient Information:

Ritodrine is used to stop premature labor. Contact your doctor immediately if
the contractions start again or water breaks.

Do not change the dose of Ritodrine of dosing schedule. Do not start any new
medication (include the prescription and non-prescription medication) without
checking with your doctor.

 

Yutopar S.R Interactions

Ritodrine may interact with the folloing medications:
-Anesthetics: may potentiate the hypotensive effects
-Diazoxide, parenteral
-Magnesium sulfate
-Meperidine
-sympathomimetic amines: may be additive
-Beta-adrenergic antagonists: inhibit Ritodrine
-Corticosteroids: may cause pulmonary edema

 

Yutopar S.R Contraindications

Ritodrine should not be giving to patient under the following medical conditions
(except special situations):
-pregnancy less than 20 weeks
-antepartum hemorrhage which demands immediate delivery
-eclampsia and severe preeclampsia
-intra-uterine fetal death
-chorioamnionitis
-maternal cardiac disease
-pulmonary hypertension
-maternal hyperthyroidism
-uncontrolled maternal diabetes mellitus
-pre-existing maternal medical conditions:
*hypovolemia
*cardiac arrhythmias associated with tachycardia or digitalis intoxication
*uncontrolled hypertension
*pheochromocytoma
*bronchial asthma already treated by betamimetics and/or steroids
*known hypersensitivity to any component of the product
*parenteral ritodrine: history of hypersensitivity to sulfite
*asthma patients may react with bronchospasm and anaphylactic shock.

 

Additional information about Yutopar S.R

Yutopar S.R Indication: For the treatment and prophylaxis of premature labour Mechanism Of Action: Yutopar S.R is beta-2 adrenergic agonist. It binds to beta-2 adrenergic receptors on outer membrane of myometrial cell, activates adenyl cyclase to increase the level of cAMP which decreases intracellular calcium and leads to a decrease of uterine contractions. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Ritodrine Synonyms: Ritodrina [Inn-Spanish]; Ritodrine Hcl; Ritodrine Hydrochloride; Ritodrinium [Inn-Latin] Drug Category: Adrenergic beta-Agonists; Tocolytic Agents; Sympathomimetic Drug Type: Small Molecule; Approved Other Brand Names containing Ritodrine: Yutopar; Yutopar S.R; Absorption: Not Available Toxicity (Overdose): LD50=64mg/kg (mice, IV); LD50=540 mg/kg (mice, oral); LD50=85 mg/kg (rat, IV) Protein Binding: ~56% Biotransformation: Hepatic, by both the mother and fetus Half Life: 1.7-2.6 hours Dosage Forms of Yutopar S.R: Not Available Chemical IUPAC Name: 4-[(1R,2S)-1-hydroxy-2-[2-(4-hydroxyphenyl)ethylamino]propyl]phenol Chemical Formula: C17H21NO3 Ritodrine on Wikipedia: https://en.wikipedia.org/wiki/Ritodrine Organisms Affected: Humans and other mammals